LRP6 Polyclonal Antibody

CAT: 0866-RD90114A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90114A-01Size:60 μL
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Background
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Description
This is a LRP6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
LRP6, ADCAD2, STHAG7
Gene ID
4040
Swiss Prot
O75581
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human LRP6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55kDa
Observed Molecular Weight
55KDa
Host or Source
Rabbit
Isotype
IgG

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