CACNB4 Polyclonal Antibody

• Background :

  This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME) . Multiple transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a CACNB4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CACNB4, CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6

• Gene ID :

  785

• Swiss Prot :

  O00305

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human CACNB4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:1000-1:2000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  59kDa/61kDa

• Observed Molecular Weight :

  70kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG