TBC1D23 Polyclonal Antibody

CAT: 0866-RD89970A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89970A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning (By similarity. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS challenge (By similarity.
Description
This is a TBC1D23 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
TBC1D23, NS4ATP1
Gene ID
55773
Swiss Prot
Q9NUY8
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human TBC1D23
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22kDa/27kDa/29kDa/30kDa/31kDa
Observed Molecular Weight
31kDa
Host or Source
Rabbit
Isotype
IgG

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