CLPB Polyclonal Antibody

• Background :

  This gene belongs to the ATP-ases associated with diverse cellular activities (AAA+) superfamily. Members of this superfamily form ring-shaped homo-hexamers and have highly conserved ATPase domains that are involved in various processes including DNA replication, protein degradation and reactivation of misfolded proteins. All members of this family hydrolyze ATP through their AAA+ domains and use the energy generated through ATP hydrolysis to exert mechanical force on their substrates. In addition to an AAA+ domain, the protein encoded by this gene contains a C-terminal D2 domain, which is characteristic of the AAA+ subfamily of Caseinolytic peptidases to which this protein belongs. It cooperates with Hsp70 in the disaggregation of protein aggregates. Allelic variants of this gene are associated with 3-methylglutaconic aciduria, which causes cataracts and neutropenia. Alternative splicing results in multiple transcript variants.

• Description :

  This is a CLPB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CLPB, ANKCLB, HSP78, MEGCANN, MGCA7, SKD3

• Gene ID :

  81570

• Swiss Prot :

  Q9H078

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human CLPB

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  17kDa

• Observed Molecular Weight :

  14kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG