MAP3K12 Polyclonal Antibody

• Background:

  This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

• Description:

  This is a MAP3K12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1

• Gene ID:

  7786

• Swiss Prot:

  Q12852

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human MAP3K12

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  79kDa/82kDa/96kDa

• Observed Molecular Weight:

  120kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG