BRCC3 Polyclonal Antibody

CAT: 0866-RD89847A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89847A-01Size:60 μL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.
Description
This is a BRCC3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BRCC3, BRCC36, C6.1A, CXorf53
Gene ID
79184
Swiss Prot
P46736
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human BRCC3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
68kDa
Observed Molecular Weight
80kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RD81942A-01Polyclonal AntibodyPC1 Polyclonal Antibody
RD83593A-01Polyclonal AntibodyPC4 Polyclonal Antibody
RD267576A-01CDK14 Polyclonal Antibody
RD267670A-01CD68 Polyclonal Antibody
RD267614A-01CLINT1 Polyclonal Antibody
RD267767A-01GRK1 Polyclonal Antibody
RD265847A-01YAP1 Polyclonal Antibody
RD265848A-01β-catenin Polyclonal Antibody
RD240344A-01IL6R Polyclonal Antibody
RD70063A-01TCP1 Polyclonal Antibody

Alternative Products

CatalogName
CAC07488-01Brcc3 Polyclonal Antibody
NBP1-76831Rabbit Polyclonal BRCC3 Antibody
E10G01134BRCC3 Rabbit Polyclonal Antibody
H00079184-B01PMouse Polyclonal BRCC3 Antibody
bs-14278R-01DEPDC1B/BRCC3 Polyclonal Antibody
HA695014-01Anti-BRCC3 Polyclonal Antibody
TA306473BRCC36 (BRCC3) Rabbit Polyclonal Antibody
bs-6888R-APCBRCC3 Polyclonal Antibody, APC Conjugated
bs-6888R-BiotinBRCC3 Polyclonal Antibody, Biotin Conjugated
MBS8517257-01BRCC3 Antibody

Popular Products