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PIAS4 Polyclonal Antibody

CAT: 0866-RD89666A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89666A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Functions as an E3-type small ubiquitin-like modifier (SUMO ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
Description
This is a PIAS4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PIAS4, PIAS-gamma, PIASY, Piasg, ZMIZ6
Gene ID
51588
Swiss Prot
Q8N2W9
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human PIAS4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
10kDa
Observed Molecular Weight
13kDa
Host or Source
Rabbit
Isotype
IgG

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