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CLASP2 Polyclonal Antibody

CAT: 0866-RD89627A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89627A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Description
This is a CLASP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CLASP2
Gene ID
23122
Swiss Prot
O75122
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human CLASP2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
113kDa
Observed Molecular Weight
114kDa/125kDa
Host or Source
Rabbit
Isotype
IgG

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