CDK5 Polyclonal Antibody

• Background:

  This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.

• Description:

  This is a CDK5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CDK5, LIS7, PSSALRE

• Gene ID:

  1020

• Swiss Prot:

  Q00535

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CDK5

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  24kDa

• Observed Molecular Weight:

  27KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG