COL4A4 Polyclonal Antibody

• Background :

  This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease) . Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR.

• Description :

  This is a COL4A4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  BFH, ATS2, CA44

• Gene ID :

  1286

• Swiss Prot :

  P53420

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human COL4A4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  40kDa

• Observed Molecular Weight :

  39KDa

• Host or Source :

  Rabbit

• Isotype :

  IgG