CDK2AP1 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Description:

  This is a CDK2AP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CDK2AP1, DOC1, DORC1, ST19, doc-1, p12DOC-1, cyclin-dependent kinase 2-associated protein 1

• Gene ID:

  8099

• Swiss Prot:

  O14519

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human CDK2AP1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  55kDa/58kDa/59kDa/60kDa/61kDa/62kDa/65kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG