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TTLL12 Polyclonal Antibody

CAT: 0866-RD89393A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89393A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3. Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.
Description
This is a TTLL12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
TTLL12, dJ526I14.2, tubulin tyrosine ligase like 12
Gene ID
23170
Swiss Prot
Q14166
Reactivity
Human
Immunogen
Recombinant fusion protein of human TTLL12
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
31kDa/37kDa/42kDa/44kDa/52kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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