Products for Research Use Only

G6PC Polyclonal Antibody

CAT: 0866-RD89369A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89369A-01Size:60 μL
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Background
Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1) . This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.
Description
This is a G6PC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
G6PC, G6PT, GSD1, GSD1a, G6Pase
Gene ID
2538
Swiss Prot
P35575
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide of human G6PC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
410kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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