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PRDM9 Polyclonal Antibody

CAT: 0866-RD89262A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89262A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described.
Description
This is a PRDM9 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PFM6, KMT8B, MSBP3, ZNF899, MEISETZ
Gene ID
56979
Swiss Prot
Q9NQV7
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PRDM9
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26kDa
Observed Molecular Weight
30kDa
Host or Source
Rabbit
Isotype
IgG

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