PANK2 Polyclonal Antibody

• Background:

  This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

• Description:

  This is a PANK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  C20orf48, HARP, HSS, NBIA1, PKAN, PANK2

• Gene ID:

  80025

• Swiss Prot:

  Q9BZ23

• Reactivity:

  Mouse

• Immunogen:

  A synthetic peptide of human PANK2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Observed Molecular Weight:

  40KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG