SHANK2 Polyclonal Antibody

CAT: 0866-RD89081A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89081A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Description
This is a SHANK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3, SHANK2
Gene ID
22941
Swiss Prot
Q9UPX8
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SHANK2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
227kDa
Observed Molecular Weight
250kDa
Host or Source
Rabbit
Isotype
IgG

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