MT-CO3 Polyclonal Antibody

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS are transferred via the dinuclear copper A center (CU (A of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC formed by heme A3 and copper B (CU (B. The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

This is a MT-CO3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

COIII, MTCO3, COX3, MT-CO3

4514

P00414

Human, Mouse, Rat

A synthetic peptide of human MT-CO3

Unconjugated

Polyclonal Antibody

WB

Affinity purification

Antibody

1mg/mL

WB 1:500-1:2000

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

56kDa

65kDa

Rabbit