A2ML1 Polyclonal Antibody

• Background:

  This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888) . Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085) . Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

• Description:

  This is a A2ML1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CPAMD9, p170, A2ML1

• Gene ID:

  144568

• Swiss Prot:

  A8K2U0

• Reactivity:

  Human, Rat

• Immunogen:

  A synthetic peptide of human A2ML1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  45kDa

• Observed Molecular Weight:

  46kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG