RASD2 Polyclonal Antibody

• Background:

  This gene belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The encoded protein functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO) . This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD) . Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.

• Description:

  This is a RASD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Rhes, TEM2, MGC:4834, RASD2

• Gene ID:

  23551

• Swiss Prot:

  Q96D21

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human RASD2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  11kDa

• Observed Molecular Weight:

  10KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG