PCGF2 Polyclonal Antibody

• Background:

  The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

• Description:

  This is a PCGF2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PCGF2, MEL-18, RNF110, ZNF144

• Gene ID:

  7703

• Swiss Prot:

  P35227

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein of human PCGF2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  54kDa/55kDa/59kDa

• Observed Molecular Weight:

  54kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG