RNF20 Polyclonal Antibody

• Background:

  The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS) .

• Description:

  This is a RNF20 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  RNF20, BRE1, BRE1A, hBRE1

• Gene ID:

  56254

• Swiss Prot:

  Q5VTR2

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human RNF20

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  144kDa

• Observed Molecular Weight:

  144kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG