Products for Research Use Only

RNF20 Polyclonal Antibody

CAT: 0866-RD88802A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD88802A-01Size:60 μL
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Background
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS) .
Description
This is a RNF20 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
RNF20, BRE1, BRE1A, hBRE1
Gene ID
56254
Swiss Prot
Q5VTR2
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human RNF20
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
144kDa
Observed Molecular Weight
144kDa
Host or Source
Rabbit
Isotype
IgG