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ATF6B Polyclonal Antibody

CAT: 0866-RD88668A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD88668A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Description
This is a ATF6B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ATF6B, CREB-RP, CREBL1, G13
Gene ID
1388
Swiss Prot
Q99941
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human ATF6B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
192kDa
Observed Molecular Weight
250kDa
Host or Source
Rabbit
Isotype
IgG

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