UGT1A10 Polyclonal Antibody

• Background:

  This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.

• Description:

  This is a UGT1A10 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J

• Gene ID:

  54575

• Swiss Prot:

  Q9HAW8

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human UGT1A10

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  18kDa/20kDa

• Observed Molecular Weight:

  21kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG