Products for Research Use Only

NPRL2 Polyclonal Antibody

CAT: 0866-RD88592A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD88592A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Description
This is a NPRL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NPRL2, FFEVF2, NPR2, NPR2L, TUSC4, NPR2-like
Gene ID
10641
Swiss Prot
Q8WTW4
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human NPRL2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29kDa/45kDa
Observed Molecular Weight
45kDa
Host or Source
Rabbit
Isotype
IgG