UBE2E2 Polyclonal Antibody

• Background:

  Ube2E2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 96% identical amino acid sequence with Ube2E1 and Ube2E3 with the exception of the N-terminal extension that has little in common with the other two E2s. Ube2E2 interacts with ARA54 and RNF8. The RNF8/ Ube2E2 interaction is found to catalyze K48-linked poly-ubiquitination. Ube2E2 may play a role in ubiquitination and subsequent proteasomal degradation of the E3 Ub ligase Parkin.

• Description:

  This is a UBE2E2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  UBE2E2, UBCH8

• Gene ID:

  7325

• Swiss Prot:

  Q96LR5

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human UBE2E2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  61kDa

• Observed Molecular Weight:

  71kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG