NR1H2 Polyclonal Antibody

• Background:

  The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]) .[supplied by OMIM, Jan 2010]

• Description:

  This is a NR1H2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  NR1H2, LXR-b, LXRB, NER, NER-I, RIP15, UNR

• Gene ID:

  7376

• Swiss Prot:

  P55055

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human NR1H2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  30kDa/31kDa/33kDa

• Observed Molecular Weight:

  31kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG