SDHD Polyclonal Antibody

• Background:

  This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.

• Description:

  This is a SDHD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SDHD, CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS

• Gene ID:

  6392

• Swiss Prot:

  O14521

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human SDHD

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  74kDa/83kDa/88kDa/92kDa

• Observed Molecular Weight:

  110kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG