EDARADD Polyclonal Antibody

• Background :

  This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

• Description :

  This is a EDARADD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  EDARADD, ECTD11A, ECTD11B, ED3, EDA3

• Gene ID :

  128178

• Swiss Prot :

  Q8WWZ3

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human EDARADD

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  20kDa/31kDa

• Observed Molecular Weight :

  32kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG