GNPTAB Polyclonal Antibody

CAT: 0866-RD88378A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD88378A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572) . In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.
Description
This is a GNPTAB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GNPTAB, GNPTA, ICD
Gene ID
79158
Swiss Prot
Q3T906
Reactivity
Human
Immunogen
Recombinant fusion protein of human GNPTAB
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
18kDa/30kDa
Observed Molecular Weight
30KDa
Host or Source
Rabbit
Isotype
IgG

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