RNF170 Polyclonal Antibody

• Background:

  This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.

• Description:

  This is a RNF170 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  RNF170, ADSA, SNAX1

• Gene ID:

  81790

• Swiss Prot:

  Q96K19

• Reactivity:

  Mouse

• Immunogen:

  Recombinant fusion protein of human RNF170

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  32kDa/40kDa/47kDa

• Observed Molecular Weight:

  47kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG