SLC7A8 Polyclonal Antibody

CAT: 0866-RD88024A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD88024A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (reabsorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg when administered as the L-cysteine or D, L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Description
This is a SLC7A8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SLC7A8, LAT2, LPI-PC1
Gene ID
23428
Swiss Prot
Q9UHI5
Reactivity
Human
Immunogen
A synthetic peptide of human SLC7A8
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42kDa/46kDa/48kDa/50kDa/56kDa
Observed Molecular Weight
56kDa
Host or Source
Rabbit
Isotype
IgG

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