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ITM2B Polyclonal Antibody

CAT: 0866-RD88008A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD88008A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Description
This is a ITM2B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ITM2B, ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, RDGCA, imBRI2
Gene ID
9445
Swiss Prot
Q9Y287
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human ITM2B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
71kDa/77kDa/83kDa/111kDa/117kDa/120kDa/122kDa
Observed Molecular Weight
123kDa
Host or Source
Rabbit
Isotype
IgG

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