APPL2 Polyclonal Antibody

CAT: 0866-RD87942A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87942A-01Size:60 μL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain, and a C-terminal phosphotyrosine binding (PTB) domain, and they bind the Rab5 through the BAR domain. They are associated with endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus. They interact with the NuRD/MeCP1 complex (nucleosome remodeling and deacetylase /methyl-CpG-binding protein 1 complex) and are required for efficient cell proliferation. A chromosomal aberration t (12;22) (q24.1; q13.3) involving this gene and the PSAP2 gene results in 22q13.3 deletion syndrome, also known as Phelan-McDermid syndrome.
Description
This is a APPL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
APPL2, DIP13B
Gene ID
55198
Swiss Prot
Q8NEU8
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human APPL2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28kDa/31kDa
Observed Molecular Weight
31kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RD75083A-01APPL1 Polyclonal Antibody
RD83116A-01APPL1 Polyclonal Antibody
RD81942A-01Polyclonal AntibodyPC1 Polyclonal Antibody
RD83593A-01Polyclonal AntibodyPC4 Polyclonal Antibody
RD266124A-01IL13 Polyclonal Antibody
RD267135A-01MDM4 Polyclonal Antibody
RD267611A-01UBE2L6 Polyclonal Antibody
RD77560A-01PLAUR Polyclonal Antibody
RD78741A-01EIF2AK2 Polyclonal Antibody
RD76447A-01ADHFE1 Polyclonal Antibody

Alternative Products

CatalogName
MBS8569284-01APPL2 Polyclonal Antibody
MBS9440233-01APPL2 Polyclonal Conjugated Antibody
E28PN8095APPL2 Rabbit Polyclonal Antibody
TA361524DIP13B (APPL2) Rabbit Polyclonal Antibody
MBS398024-01Adaptor Protein, Phosphotyrosine Interacting with PH Domain And Leucine Zipper 2 (Appl2): Human, rabbit polyclonal (Antibody)
E306445APPL2 Antibody
PAab00517Anti-APPL2 antibody
CSB-CL818777HUAPPL2

Popular Products