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TRMT112 Polyclonal Antibody

CAT: 0866-RD87843A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87843A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N (7 position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with HEMK2/N6AMT1 also monomethylates 'Lys-12' of histone H4 (H4K12me1. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.
Description
This is a TRMT112 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
TRMT112, HSPC152, HSPC170, TRM112, TRMT11-2, hTrm112
Gene ID
51504
Swiss Prot
Q9UI30
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human TRMT112
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
64kDa/66kDa
Observed Molecular Weight
75kDa
Host or Source
Rabbit
Isotype
IgG

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