TRMT112 Polyclonal Antibody

• Background:

  Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N (7 position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with HEMK2/N6AMT1 also monomethylates 'Lys-12' of histone H4 (H4K12me1. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.

• Description:

  This is a TRMT112 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TRMT112, HSPC152, HSPC170, TRM112, TRMT11-2, hTrm112

• Gene ID:

  51504

• Swiss Prot:

  Q9UI30

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human TRMT112

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  64kDa/66kDa

• Observed Molecular Weight:

  75kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG