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FAM3B Polyclonal Antibody

CAT: 0866-RD87803A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87803A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FAM3B, also known as Pancreatic-derived factor (PANDER), is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B can induce apoptosis of alpha and beta cells in a dose- and time-dependent manner. Previous studies showed that FAM3B regulates glucose and lipid metabolism through interaction with liver and endocrine pancreas. FAM3B silencing activates both extrinsic and intrinsic apoptotic pathways. In general, silencing FAM3B promoted p53 phosphorylation and induced p53 accumulation by decreasing Mdm2 expression, which resulted in apoptotic cell death.
Description
This is a FAM3B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
FAM3B,2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44
Gene ID
54097
Swiss Prot
P58499
Reactivity
Mouse
Immunogen
Recombinant fusion protein of human FAM3B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70kDa/86kDa/92kDa
Observed Molecular Weight
71kDa
Host or Source
Rabbit
Isotype
IgG

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