AIRE Polyclonal Antibody

• Background :

  This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED) .

• Description :

  This is a AIRE Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  AIRE, AIRE1, APECED, APS1, APSI, PGA1

• Gene ID :

  326

• Swiss Prot :

  O43918

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human AIRE

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  51kDa/52kDa

• Observed Molecular Weight :

  50kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG