SLAMF7 Polyclonal Antibody

CAT: 0866-RD87788A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87788A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed on the surface of NK cells, CD8+ T cells, activated B cells, and mature dendritic cells but not in promyelocytic, B-cell lines, or T-cell lines. In human NK cells, activated SLAMF7 transmits signals following association with the adaptor protein EAT-2 . In the absence of EAT-2, SLAMF7 potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.
Description
This is a SLAMF7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SLAMF7,19A, CD319, CRACC, CS1
Gene ID
57823
Swiss Prot
Q9NQ25
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human SLAMF7
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29kDa/33kDa/34kDa
Observed Molecular Weight
45kDa
Host or Source
Rabbit
Isotype
IgG

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