MESDC2 Polyclonal Antibody

• Background:

  Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.

• Description:

  This is a MESDC2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MESDC2, BOCA, MESD

• Gene ID:

  23184

• Swiss Prot:

  Q14696

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human MESDC2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  48kDa

• Observed Molecular Weight:

  49kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG