RNF144B Polyclonal Antibody

• Background :

  E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.

• Description :

  This is a RNF144B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  RNF144B, IBRDC2, PIR2, bA528A10.3, p53RFP

• Gene ID :

  255488

• Swiss Prot :

  Q7Z419

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human RNF144B

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  35kDa

• Observed Molecular Weight :

  35kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG