TLE1 Polyclonal Antibody

• Background :

  Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

• Description :

  This is a TLE1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  TLE1, ESG, ESG1, GRG1

• Gene ID :

  7088

• Swiss Prot :

  Q04724

• Reactivity :

  Mouse

• Immunogen :

  Recombinant fusion protein of human TLE1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  42kDa/43kDa/45kDa

• Observed Molecular Weight :

  44kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG