TLE1 Polyclonal Antibody

• Background:

  Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

• Description:

  This is a TLE1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TLE1, ESG, ESG1, GRG1

• Gene ID:

  7088

• Swiss Prot:

  Q04724

• Reactivity:

  Mouse

• Immunogen:

  Recombinant fusion protein of human TLE1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  42kDa/43kDa/45kDa

• Observed Molecular Weight:

  44kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG