Products for Research Use Only

Rubicon Polyclonal Antibody

CAT: 0866-RD87644A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87644A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Description
This is a Rubicon Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
RUBCN, KIAA0226, RUBICON, SCAR15
Gene ID
9711
Swiss Prot
Q92622
Reactivity
Mouse
Immunogen
Recombinant fusion protein of human Rubicon
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
12kDa/70kDa/79kDa/86kDa
Observed Molecular Weight
87kDa
Host or Source
Rabbit
Isotype
IgG