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GDF5 Polyclonal Antibody

CAT: 0866-RD87643A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87643A-01Size:60 μL
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Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.
Description
This is a GDF5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GDF5, BDA1C, BMP-14, BMP14, CDMP1, LAP-4, LAP4, OS5, SYM1B, SYNS2
Gene ID
8200
Swiss Prot
P43026
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide of human GDF5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
102kDa/103kDa/108kDa
Observed Molecular Weight
108kDa
Host or Source
Rabbit
Isotype
IgG

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