ASPH Polyclonal Antibody

CAT: 0866-RD87636A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87636A-01Size:60 μL
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Background
This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF) -like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.
Description
This is a ASPH Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ASPH, AAH, BAH, CASQ2BP1, FDLAB, HAAH, JCTN, junctin
Gene ID
444
Swiss Prot
Q12797
Reactivity
Human
Immunogen
Recombinant fusion protein of human ASPH
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
166kDa
Observed Molecular Weight
169kDa
Host or Source
Rabbit
Isotype
IgG

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