MSL2 Polyclonal Antibody

• Background:

  Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.

• Description:

  This is a MSL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MSL2, MSL-2, MSL2L1, RNF184

• Gene ID:

  55167

• Swiss Prot:

  Q9HCI7

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human MSL2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  113kDa/115kDa

• Observed Molecular Weight:

  115kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG