MSL2 Polyclonal Antibody

• Background :

  Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.

• Description :

  This is a MSL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  MSL2, MSL-2, MSL2L1, RNF184

• Gene ID :

  55167

• Swiss Prot :

  Q9HCI7

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human MSL2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  113kDa/115kDa

• Observed Molecular Weight :

  115kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG