DAAM1 Polyclonal Antibody

• Background:

  Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl) -Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins.

• Description:

  This is a DAAM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  DAAM1

• Gene ID:

  23002

• Swiss Prot:

  Q9Y4D1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human DAAM1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  47kDa/50kDa

• Observed Molecular Weight:

  51KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG