EBF1 Polyclonal Antibody
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EBF1 Polyclonal Antibody
Background:
Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity.Description:
This is a EBF1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.Synonyms:
EBF1, COE1, EBF, O/E-1, OLF1Gene ID:
1879Swiss Prot:
Q9UH73Reactivity:
HumanImmunogen:
A synthetic peptide of human EBF1Clonality:
PolyclonalConjugation:
UnconjugatedType:
Polyclonal AntibodyApplications:
WBPurification Method:
Affinity purificationAssay Type:
AntibodyConcentration:
1mg/mLDilution:
WB 1:500-1:2000Buffer:
PBS with 0.01% thiomersal,50% glycerol, pH7.3.Storage Conditions:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.Calculated Molecular Weight:
123kDaObserved Molecular Weight:
190kDaHost or Source:
RabbitIsotype:
IgG
