PKLR Polyclonal Antibody

• Background :

  The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA) . Multiple transcript variants encoding different isoforms have been found for this gene.

• Description :

  This is a PKLR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  PKLR, PK1, PKL, PKR, PKRL, RPK

• Gene ID :

  5313

• Swiss Prot :

  P30613

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human PKLR

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  22kDa

• Observed Molecular Weight :

  26kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG