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PADI2 Polyclonal Antibody

CAT: 0866-RD87438A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD87438A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
Description
This is a PADI2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PADI2, PAD-H19, PAD2, PDI2
Gene ID
11240
Swiss Prot
Q9Y2J8
Reactivity
Human
Immunogen
Recombinant fusion protein of human PADI2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44kDa/45kDa/55kDa/58kDa
Observed Molecular Weight
54kDa
Host or Source
Rabbit
Isotype
IgG

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