HTR2C Polyclonal Antibody

CAT: 0866-RD87369A-01Size: 120 μLDry Ice: NoHazardous: No
CAT#:0866-RD87369A-01Size:120 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.
Description
This is a HTR2C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HTR2C,5-HT1C,5-HT2C,5-HTR2C,5HTR2C, HTR1C
Gene ID
3358
Swiss Prot
P28335
Reactivity
Human
Immunogen
A synthetic peptide of human HTR2C
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
16kDa
Observed Molecular Weight
17KDa
Host or Source
Rabbit
Isotype
IgG

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