MAP4K4 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

• Description :

  This is a MAP4K4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  MAP4K4, FLH21957, HEL-S-31, HGK, MEKKK4, NIK

• Gene ID :

  9448

• Swiss Prot :

  O95819

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human MAP4K4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  298kDa/304kDa

• Observed Molecular Weight :

  290kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG