MAP4K4 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

• Description:

  This is a MAP4K4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MAP4K4, FLH21957, HEL-S-31, HGK, MEKKK4, NIK

• Gene ID:

  9448

• Swiss Prot:

  O95819

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human MAP4K4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  298kDa/304kDa

• Observed Molecular Weight:

  290kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG